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altona SARS-CoV-2 test kits reactivity analyses in response to mutations

 

 

 

 

Reactivity of molecular diagnostic tests is determined by the sequences of the oligonucleotides contained in the reaction mix. RNA viruses in particular have an inherently high mutation rate leading to changes in the genome sequence during every replication event. SARS-CoV-2 is no exception. We at altona Diagnostics are well aware of the importance to constantly monitor the emerging and circulating sequences and we update the reactivity analysis of our assays on a regular basis. Mutations in the viral genome occur in every gene and untranslated region and are not limited to the S gene. Our S gene assay is located in a conserved region coding for the membrane fusion subunit (domain 2) of the spike protein. Until now, we have not found any mutations that would cause our S gene assay to fail.  

 

Download PDF with latest results from current altona reactivity investigations (May 31, 2021)

 

 

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